美国芝加哥大学肿瘤研究所 博士后/ University of Chicago Ben May Institute for Cancer Research Post-doctoral Fellow
美国西北大学医学院 博士后/Northwestern University Feinberg School of Medicine Post-doctoral Fellow
Jiaqi Sun, Xiyang Wang, Qingsong Shen, Min Wang, Shuxian Chen, Xuechun Zhang, Yongping Huang, Zhonglin Zhang, Wenhua Li, Yufeng Yuan;, Zan Huang; DNASE1L3 inhibits hepatocellular carcinoma by delaying cell cycle progression through CDK2. Cellular Oncology, Accepted
Hu, Yufeng#; He, Wenzhi#; Huang, Yongping#; Xiang, Hui; Guo, Juan; Che, Yan; Cheng, Xu; Hu, Fengjiao; Hu, Manli; Ma, Tengfei; Yu, Jie; Tian, Han; Tian, Song; Ji, Yan-Xiao; Zhang, Peng; She, Zhi-Gang; Zhang, Xiao-Jing; Huang, Zan*; Yang, Juan*; Li, Hongliang*; Fatty Acid Synthase-Suppressor Screening Identifies Sorting Nexin 8 as a Therapeutic Target for NAFLD. Hepatology, 2021, 74(5): 2508-2525.
Yan, Zhen-Zhen#; Huang, Yong-Ping#; Wang, Xin#; Wang, Hai-Ping; Ren, Fei; Tian, Rui-Feng; Cheng, Xu; Cai, Jie; Zhang, Yan; Zhu, Xue-Yong; She, Zhi-Gang; Zhang, Xiao-Jing; Huang, Zan*; Li, Hongliang*; Integrated Omics Reveals Tollip as an Regulator and Therapeutic Target for Hepatic Ischemia-Reperfusion Injury in Mice., Hepatology, 2019, 70(5): 1750-1769.
Yang, Xuejing#; Lu, Bin#; Sun, Xueqin#; Han, Cuijuan; Fu, Chunling; Xu, Kailin; Wang, Min; Li, Dengju; Chen, Zhichao; Opal, Puneet; Wen, Qiang; Crispino, John D; Wang, Qian-Fei*; Huang, Zan*; ANP32A regulates histone H3 acetylation and promotes leukemogenesis. Leukemia, 2018, 32(7): 1587-1597.
Ji YX#, Huang Z#, Yang X#, Wang X#, Zhao LP, Wang PX, Zhang XJ, Alves-Bezerra M, Cai L, Zhang P, Lu YX, Bai L, Gao MM, Zhao H, Tian S, Wang Y, Huang ZX, Zhu XY, Zhang Y, Gong J, She ZG, Li F, Cohen DE & Li H. The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis. Nat Med. 2018.
Yan FJ, Zhang XJ, Wang WX, Ji YX, Wang PX, Yang Y, Gong J, Shen LJ, Zhu XY, Huang Z* & Li H*. The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis. Hepatology. 2017;65(5):1492-1511.
Wang X, Mao W, Fang C, Tian S, Zhu X, Yang L, Huang Z* & Li H*. Dusp14 protects against hepatic ischaemia-reperfusion injury via Tak1 suppression. J Hepatol. 2017.
Lu B, Ren Y, Sun X, Han C, Wang H, Chen Y, Peng Q, Cheng Y, Cheng X, Zhu Q, Li W, Li HL, Du HN, Zhong B*, Huang Z*. Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3. Cell Host Microbe. 2017;22(1):86-98 e84.
Yan FJ, Zhang XJ, Wang WX, Ji YX, Wang PX, Yang Y, Gong J, Shen LJ, Zhu XY, Huang Z*, Li H*. The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis. Hepatology. 2017;65(5):1492-1511.
Jin Q, Ren Y, Wang M, Suraneni PK, Li D, Crispino JD, Fan J*, Huang Z*. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6(9):e478.
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, Li Y, Zhou Y, Li W, Huang Z*. Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation. Cellular and Molecular Life Sciences: CMLS. 2015. 72(4): 821-832
Lin Y, Li D, Liang Q, Liu S, Zuo X, Li L, Sun X, Li W, Guo M*, Huang Z*. miR-638 Regulates Differentiation and Proliferation in Leukemic Cells by Targeting Cyclin-dependent Kinase 2. J Biol Chem. 2015. 290(3): 1818-1828
Sun X, Lu B, Hu B, Xiao W, Li W, Huang Z#. Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling. Blood Cancer J.2014. 4: e198
Liu L, Wen Q, Gong R, Gilles L, Stankiewicz MJ, Li W, Guo M, Li L, Sun X, Crispino JD, Huang Z*. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death & Disease. 2014. 5: e988
Wang W, Cai J, Wu Y, Hu L, Chen Z, Hu J, Li W, Guo M*, Huang Z*. Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1. Cellular and Molecular Life Sciences: CMLS.2013. 70(20): 3947-3958
Khan I#, Huang Z#, Wen Q, Stankiewicz MJ, Gilles L, Goldenson B, Schultz R, Diebold L, Gurbuxani S, Finke CM, Lasho TL, Koppikar P, Pardanani A, Stein B, Altman JK, Levine RL, Tefferi A, Crispino JD. AKT is a therapeutic target in myeloproliferative neoplasms. Leukemia.2013. 27(9): 1882-1890
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD. Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL. Cell.2012. 150(3): 575-589
Wang W, Guo M, Hu L, Cai J, Zeng Y, Luo J, Shu Z, Li W*, Huang Z*. The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-kappaB signaling. J Biol Chem.2012. 287(51): 42856-42866
Huang Z, Dore LC, Li Z, Orkin SH, Feng G, Lin S, Crispino JD. GATA-2 reinforces megakaryocyte development in the absence of GATA-1. Mol Cell Biol. 2009;29(18):5168-5180.
Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. J Clin Invest. 2007;117(12):3890-3899.
